01/06/2026
If your digestion suddenly feels unpredictable in perimenopause, you’re not imagining it.
For many women, the gut is one of the first systems to shift as hormones fluctuate — often before cycles stop and before labs look abnormal.
Changes in estrogen, cortisol, and the microbiome can affect:
🌀 digestion
🩸 blood sugar response
🔥 inflammation
🧠 mood and sleep
This isn’t about willpower or “doing something wrong.”
It’s physiology.
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