05/11/2026
APIC is continuing to monitor an outbreak of the Andes strain of hantavirus associated with a Dutch-flagged cruise ship (MV Hondius) that traveled from Ushuaia, Argentina, across the South Atlantic in April 2026.
Below is an update on the current state of this outbreak, as well as the guidance available for response.
๐๐ฎ๐ซ๐ซ๐๐ง๐ญ ๐๐ข๐ญ๐ฎ๐๐ญ๐ข๐จ๐ง:
โข As of May 11, 2026: 9 cases (7 laboratory-confirmed and 2 probable) have been reported internationally, including 3 deaths.
โข To date, all identified cases were passengers on the cruise ship.
โข The causative virus is Andes virus (ANDV), which can cause hantavirus pulmonary syndrome (HPS) and is the only hantavirus known to have limited person-to-person transmission, typically requiring close, prolonged contact. The Andes virus is endemic in Argentina and Chile but not in the United States.
โข WHO, CDC, and ECDC assess the risk to the general public as low; risk to passengers and crew is considered moderate.
๐๐ฅ๐ข๐ง๐ข๐๐๐ฅ ๐๐จ๐ง๐ฌ๐ข๐๐๐ซ๐๐ญ๐ข๐จ๐ง๐ฌ:
โข Incubation: 4โ42 days
โข Early symptoms: fever, myalgia, headache, gastrointestinal symptoms
โข Severe disease: rapidly progressive pneumonia, ARDS, shock
โข Case fatality: ~38% among those who develop respiratory disease [https://hubs.li/Q04g9h-30 ][cdc.https://hubs.li/Q04g9mD90]
๐๐ง๐๐๐๐ญ๐ข๐จ๐ง ๐๐ซ๐๐ฏ๐๐ง๐ญ๐ข๐จ๐ง & ๐๐๐ฌ๐ฉ๐จ๐ง๐ฌ๐:
โข Conduct travel screening at the time of patient presentation.
โข Report suspected cases immediately to local or state public health authorities for testing and coordination.
โข Patients with known or suspected Andes virus infection should be placed in an AIIR, and a gown, gloves, eye protection, and an N95 or higher-level respirator should be worn when entering the room.
โข Both high-risk and low-risk contacts of known and suspected cases should self-isolate (See CDC guidance link below)
๐๐จ๐ญ๐ญ๐จ๐ฆ ๐๐ข๐ง๐ ๐๐จ๐ซ ๐๐๐ฌ:
This is an outbreak involving a known virus variant with limited person-to-person transmission. Vigilance and early recognition are critical to maintaining containment, while emphasizing that the overall risk to U.S. healthcare settings remains very low at this time.
Existing resources in comments โฌ๏ธ