
05/27/2025
New study released by Lisa Mosconi, a neuroscientist who specializes in Alzheimer’s prevention, brain health and the link between hormonal health and cognitive function.
This study showed that hormonal replacement therapy may protect the female brain from Alzheimer’s and dementia, if started early enough in a woman’s perimenopausal period. The most benefits are appreciated when she starts within 10 years of menopause and before age 65.
This is especially helpful if someone has 1 one more copies of the APOE gene, which is present approximately 25% of people.
As someone who lost their father to Alzheimer’s and carries 1 copy of the APOE gene, this is indeed exciting news to me. I don’t yet need estrogen, but when I do, I’m going to put my estrogen patch on and use it until I die.
Taking hormone replacement at the right time in midlife reduces the risk of dementia and Alzheimer’s disease by 23% to 32%, a new meta-analysis found.