10/27/2025
New I-EaT Lab Research Alert!
Dry mouth (xerostomia) can make swallowing, speaking, and oral hygiene a daily challenge. Current treatments are often temporary or invasive.
One of our recent collaborative studies, published in ACS Advanced Polymer Materials, explores a noninvasive solution: a biocompatible polymer-based saliva gel that mimics natural saliva release. This study was conducted by postdoc , under the advisement of our lab PI Georgia Malandraki and Boudouris, and in collaboration with Randy Kimple, Nicole Rogus-Pulia, Cristina Paz, and Dimitri Scofield at the UW-Madison.
KEY FINDINGS
✅ The saliva-gel swells up to 400% its original volume in 6 hours (storing artificial saliva)
✅ Releases 97% of stored artificial saliva within 4 hours
✅ Is reusable across 5 cycles
✅ Designed for sustained, functional relief
Future work will focus on enhancing durability, release capacity, and human testing.
This innovative gel is a first step in our efforts to develop simple and affordable solutions for those living with chronic dry mouth.
🔗 https://pmc.ncbi.nlm.nih.gov/articles/PMC12270425/