03/13/2024
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Astrocytes Play Critical Role in Regulating Behavior
Researchers have identified a pivotal role played by a specific group of astrocytes in regulating behaviors associated with neuropsychiatric disorders.
Focusing on astrocytes that express the Crym gene in the central striatum, the study demonstrates how these cells contribute to the regulation of neural communication and behavior, particularly perseverative actions observed in disorders like autism, OCD, and Huntington’s disease.
By genetically manipulating these astrocytes in mice to reduce Crym expression, the researchers observed an increase in repetitive, purposeless behaviors, highlighting the significant impact of Crym-positive astrocytes on brain function and disorder manifestation.
This discovery not only challenges the traditional neuron-focused understanding of brain behavior but also suggests new paths for developing targeted therapies for neuropsychiatric conditions.
https://neurosciencenews.com/astrocytes-behavior-psychology-25696/
