
06/24/2025
Disturbing data continue to show that the U.S. HIV response is still not leveraging the messaging strategy as a powerful intervention. It’s time to change that.
"Although the evidence-based messaging strategy “Undetectable=Untransmittable” (U = U) can help reduce stigma and encourage Black women with HIV to engage in their care, it is underused."
"The systematic review of peer-reviewed intervention was published from 2018 to 2023. Of the 669 participants, the mean age from studies was 45.4 years, and 91% of the participants were Black women with HIV."
“Despite the emphasis on U=U as a key HIV prevention strategy since 2016, none of the included studies explicitly described U=U or U=U messaging as an intervention component,” the researchers wrote.
"U=U is a very relevant and necessary message that should be part of any intervention that addresses ART adherence, viral load suppression, stigma, and mental health. While we have accumulated a significant body of evidence over the last 10 years that supports U=U messaging, many clinicians still hesitate to convey this message, especially in the setting of viral blips or intermittent low-level viremia," said Dr. Nadine Harris.
Among Black women with HIV, who experience care disparities. U=U messaging is underused, and tailored interventions are needed to improve outcomes.