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Monday 8:30am - 5pm Tuesday 8:30am - 5pm Wednesday 8:30am - 5pm Thursday 8:30am - 5pm Friday 8:30am - 5pm

Nanoprobes

Nanoprobes is a nanotechnology company specializing in the development and applications of gold and other nanoparticles.

Gold nanoparticles, nanogold conjugates, nanogold labeling reagents; immunolabeling, xray contrast for EM, correlative and fluorescence microscopy imaging, enzyme metallography.

10/13/2025

CryoEM breakthrough! Seeing single proteins in live cells!
Check out the paper: Young et al. https://shorturl.at/LagYn The halo-Nanogold constructs are available at Nanoprobes by special order: https://nanoprobes.com

09/17/2025

A new microCT imaging method enables longitudinal tracking of primary and metastatic pancreatic tumors in a mouse model. Using VivoVist™, our new X-ray contrast agent, metastatic tumor volumes could be mapped more accurately than with ultrasound or bioluminescence - https://mailchi.mp/nanoprobes.com/vivovist-tracks-pancreatic-cancer

06/30/2025

Want bioorthognal EM labeling of tagged fusion proteins? Try Nanogold® labeling reagents, or ask about custom preparation of a Nanogold® reagent to label your HaloTag®, Clip-Tag®, SNAP-Tag® or other fusion protein. Plus - you can also label His-tags with our Ni-NTA-Nanogold® reagents - https://mailchi.mp/nanoprobes.com/one-probe-two-labels-fluoronanogoldcorrelates-em-with-immunofluorescence-in-one-step-9928185

06/15/2025

12 nm Nanogold®: the next Big Thing! Make any molecule into a 12 nm gold probe. 12 nm Nanogold® has the same selective, site-specific conjugation reactions as our 1.4 nm and 5 nm 12 nm Nanogold®. Ideal for post-embedding labeling - https://mailchi.mp/nanoprobes.com/12nm-nanogold-announcing

06/09/2025

Now available: Nanogold® - HaloTag® ligand and combined fluorescent and Nanogold® - HaloTag® ligand. Label HaloTag® fusion proteins with Nanogold® for high-resolution EM, or one-step fluorescent and gold labeling for correlative light and electron microscopy - https://mailchi.mp/nanoprobes.com/one-probe-two-labels-fluoronanogoldcorrelates-em-with-immunofluorescence-in-one-step-9929144

01/27/2025

See inside a mouse brain: microCT using VivoVist
VivoVist™ a new contrast agent for live animal imaging was used to see the blood vessel wiring in a live mouse's brain. Vessels smaller than 50 microns are seen and the "Circle of Willis" is clearly depicted. Image taken with a microCT and kindly provided by Dr. Sean Marrelli, Department of Neurology at McGovern Medical School, UTHealth (Houston, TX).

12/13/2024

Breakthrough in Cell Structure: one-Step double labeling of HaloTags® for correlative light microscopy and Cryoelectron Tomography. For the first time, scientists were able to label and identify specific proteins in a “living” (but quick frozen) cell in both the cytoplasm and nucleus using combined fluorescent and 1.4 nm Nanogold® - HaloTag® probes and a 5 nm Nanogold® - HaloTag® probe using cryo-electron tomography.- https://mailchi.mp/nanoprobes.com/one-probe-two-labels-fluoronanogoldcorrelates-em-with-immunofluorescence-in-one-step-9926773

11/19/2024

Cerebral Spinal Fluid (CSF) flow Connects to Peripheral Nerves - https://mailchi.mp/nanoprobes.com/csf-flows-to-peripheral-nerves
A: CSF was previously thought to be confined to brain and spinal cord (red). B: Using AuroVist™ gold nanoparticles from Nanoprobes, the CSF was found to connect to and bathe all peripheral nerves.

11/15/2024

Targeting Contrast for Micro-CT - learn about options for conjugation, targeting, and selective staining and contrast with our AuroVist™, VivoVist™ and EnzMet™ reagents -

Address

95 Horseblock Road, Unit 1
Yaphank, NY
11980

Opening Hours

Monday	8:30am - 5pm
Tuesday	8:30am - 5pm
Wednesday	8:30am - 5pm
Thursday	8:30am - 5pm
Friday	8:30am - 5pm

Telephone

+16312059490

Website

https://www.nanoprobes.com/

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Our Story

Nanoprobes was founded in 1990 by Dr. James F. Hainfeld, along with a group of scientists who were also alumni of Brookhaven National Laboratory. The independent research facility they formed has allowed Dr. Hainfeld and his colleagues the freedom to pursue some of the greatest challenges in research: seeking cures for cancer and other diseases.

While part of the funding for these endeavors has come from research grants, another source had to be found, as the scientific community faces ever-increasing government cutbacks. To this end, Nanoprobes began to offer many of the nanoparticle technologies developed by its members for use in other scientists' research.