17/08/2021
๐๐ฑ๐๐ซ๐๐ข๐ฌ๐ ๐ข๐ฌ ๐๐๐๐ข๐๐ข๐ง๐
โโ
๐Another awesome infographic from .eddiejo!
๐๐ผโโ๏ธโExercise is Medicine" is a mantra that is widely and irrefutably accepted by the medical community as well as the general public. It is, although, largely percieved in a more figurative manner with the simple understanding that a lifestyle incorporating exercise is good for health and is thereby, "medicine".
๐ง However, with growing knowledge of the biological mechanisms underlying the health promoting benefits of exercise, the popularized saying has developed a more literal and technical meaning. There is no question that in the world of metabolic syndrome and related diseases drug prescriptions supercede exercise prescriptions. Medical students are often taught the intricate mechanisms and biological targets for a variety of pharmacological treatments for conditions related to metabolic syndrome, but what is less emphasized is that many of these drugs are in fact exercise mimetics. In other words, they mimic a particular biological effect of exercise.
๐As exemplified by this infographic, common drugs for metabolic diseases such as, type II diabetes and dyslipidemia exert their effects on biological targets that regulate processes like lipid breakdown, glucose uptake, mitochondrial biogenesis, liver and pancreatic metabolism, and inflammation, resulting in improved MANAGEMENT of the disease (not treatment). Much of their effects are also acute and thus, perpetual use is often required.
โ
What may be less known and less communicated is that exercise is also an agonist for the very same targets, targets that are implicated in many of the physiological mechanisms through which exercise improves metabolic health. Not to mention, the benefits of exercise are largely both acute and chronic. So yes, even from a technical perspective, exercise is indeed medicine. Now only if exercise prescriptions were given more attention.