TREAD Research

TREAD Research TREAD is a large, award-winning clinical trial unit. Pioneering Clinical Trials. Empowering Health. Changing Lives. Professor Anton F.

The unit is run by Professor Lesley Burgess who has been involved in clinical trials since 1992. In addition to being a qualified medical doctor, she also has a MMed and PHD from Wits University, a post-graduate diploma in International Research Ethics from University of Cape Town and a MSc (Clinical Research) from Liverpool University. She spent a number of years sitting on the Stellenbosch University Health Research Ethics Committee and is currently a reviewer of the Clinical Trials Committee of the Medicines Control Council. Additional research experience includes Steering Committee membership, DSMB membership and she is actively involved in GCP and clinical trial training and site capacity building. Doubell is a Co- founder of TREAD and Head of Cardiology, Tygerberg Hospital and University of Stellenbosch. He completed his medical degree at the University of Stellenbosch in 1979, graduating as the top student of that year. He is the chairman of the Tygerberg branch of the South African Heart Association and a past-president of the South African Heart Association (two consecutive terms from 2000 to 2004). He currently still serves on the Exco of the South African Heart Association and is the Editor of SAHeart, the official Journal of the South African Heart Association.

Short Breath + Tired Legs?These are signs you shouldn’t ignore.When the heart struggles to pump efficiently, the body fe...
22/01/2026

Short Breath + Tired Legs?
These are signs you shouldn’t ignore.
When the heart struggles to pump efficiently, the body feels the impact:

• Less blood reaches your muscles
• Breathing becomes harder
• Walking becomes tiring
• Climbing stairs feels exhausting

These symptoms often develop slowly over months or even years and are easy to dismiss as “just getting older” or “being unfit.”
But if everyday activities are becoming harder, your heart may be asking for help.

Early detection can change outcomes.
Listen to your body. Don’t ignore the signs.

👉 Find out what clinical trials are currently running with TREAD and whether you or a loved one may qualify.

📱 066 472 5713
📧 info@treadresearch.co.za
🌐 www.treadresearch.co.za

✨ Welcome to a New Year ✨We wish our patients, staff, research participants, and partners a healthy year ahead. We remai...
31/12/2025

✨ Welcome to a New Year ✨We wish our patients, staff, research participants, and partners a healthy year ahead. We remain committed to research that supports better health and brighter futures and placing people at the centre of research.

Repeat Hospital Visits? Here’s Why It Happens.If you or someone you know has been hospitalised more than once for chest ...
27/12/2025

Repeat Hospital Visits? Here’s Why It Happens.
If you or someone you know has been hospitalised more than once for chest issues, breathlessness, infections, or fluid build-up, there may be underlying reasons:

• Blood pressure not fully controlled
• Heart pumping function weakening over time
• Fluid retention between visits
• Untreated inflammation
• Poor recovery after infection or hospitalisation

Many people don’t realise these symptoms progress slowly.
Early awareness can break the cycle of hospital admissions.

👉 Find out what clinical trials are currently running with TREAD and whether you or a loved one may qualify.

📱 066 472 5713
📧 info@treadresearch.co.za
🌐 www.treadresearch.co.za

🎄 Merry Christmas from Team TREAD 🎄As the year comes to a close, we’d like to thank our community, partners, and partici...
25/12/2025

🎄 Merry Christmas from Team TREAD 🎄
As the year comes to a close, we’d like to thank our community, partners, and participants for being part of the TREAD Research journey.
May this festive season bring you rest, reflection, and meaningful moments with those you care about most. We look forward to continuing our work together in the year ahead.

After being sick, your body needs time to recover.But if weeks or even months have passed and breathing still feels diff...
22/12/2025

After being sick, your body needs time to recover.
But if weeks or even months have passed and breathing still feels difficult, your body may not be fully healed yet.

You might notice:
• Getting out of breath more easily
• Feeling tired most of the time
• Tightness or wheezing in your chest
• Struggling to walk as far as you used to

Your heart, lungs and immune system work together. When one is still recovering, the others have to work harder too.

👉 If symptoms keep lingering, don’t brush them off.
Your body may be asking for a little extra care.

Find out more about ongoing research and support at TREAD Research.

📱 066 472 5713
📧 info@treadresearch.co.za
🌐 www.treadresearch.co.za

Many people, especially women, brush these symptoms off, but they can be early signs that your heart is under strain or ...
17/12/2025

Many people, especially women, brush these symptoms off, but they can be early signs that your heart is under strain or dealing with inflammation.

⚠️ Signs to pay attention to:
• A fast or pounding heartbeat
• Pressure or tightness in your chest
• Feeling like you can’t catch your breath
• Dizziness, especially during movement

These symptoms don’t always appear suddenly. They often build up quietly over time. If you’re noticing them more often, or they’re lasting longer than before, it’s worth paying attention.

💙 TREAD Research is currently running clinical studies and may be able to help you learn more about what’s happening with your heart.

Contact TREAD Research:
📱 066 472 5713
📧 info@treadresearch.co.za
🌐 www.treadresearch.co.za

Feeling tired all the time even after a good night’s sleep? Your heart might be working harder than you realise. ❤️‍🩹If ...
12/12/2025

Feeling tired all the time even after a good night’s sleep? Your heart might be working harder than you realise. ❤️‍🩹

If you:
• Wake up exhausted
• Run out of energy during the day
• Struggle with simple chores
• Need more rest than usual

…it could be a sign that your heart isn’t pumping oxygen around your body as well as it used to.

If this sounds familiar, don’t ignore it you may be eligible for one of our current research studies.

Our team is here to help you learn more and see if you qualify.
📞 Contact us: 066 472 5713
📩 Email: info@treadresearch.com

⚠️ Swollen Feet or Ankles? Don’t Ignore It.Swelling in the legs, feet, or even the stomach is often brushed off as “just...
08/12/2025

⚠️ Swollen Feet or Ankles? Don’t Ignore It.
Swelling in the legs, feet, or even the stomach is often brushed off as “just water retention” but it can be an important sign that your heart may be under strain.

🚨 Signs to watch for:
• Shoes suddenly feeling tighter
• Deep sock marks on your legs
• Unexplained weight gain of 1–2 kg in a week
• Abdominal bloating

If you’ve noticed any of these changes, even occasionally, it’s important to pay attention. Your body may be trying to tell you something.

TREAD Research is currently running clinical trials for qualifying participants. If you’d like to find out whether you may be eligible:

📞 Call: 021 938 0989
📱 WhatsApp: 066 472 5713
📧 Email: info@treadresearch.com

Struggling to Breathe Easily? It Might Not Be Just Getting Older.Getting out of breath quickly isn’t always normal. Some...
02/12/2025

Struggling to Breathe Easily? It Might Not Be Just Getting Older.
Getting out of breath quickly isn’t always normal. Sometimes it’s a sign your heart needs help.

🚩 Look out for:
• Getting out of breath on short walks
• Needing extra pillows to sleep comfortably
• Feeling puffed after small tasks
• A heavy or tight chest on the stairs

These can happen when your heart isn’t working as well as it should.

❤️ Don’t ignore it.
If breathing is becoming harder for you, it’s worth checking it early. Take part in one of our clinical research studies.

📞 Call: 021 938 0989
📱 WhatsApp: 066 472 5713
📧 Email: info@treadresearch.com

❤️ If you’ve experienced a heart attack and want to learn more about clinical trials or treatment options, we’d love to ...
25/11/2025

❤️ If you’ve experienced a heart attack and want to learn more about clinical trials or treatment options, we’d love to hear from you. Reach out to one of our friendly recruiters for more information and see how you can get involved. Your participation could help shape the future of heart health! ❤️

Contact Details:
📞 +27 21 931 7825 (Office)
📱 066 472 5713 (WhatsApp)
📧 info@treadresearch.com

💙 Have You Been Diagnosed With Diabetes?We're here to help you navigate your journey.If you’d like to learn more about o...
18/11/2025

💙 Have You Been Diagnosed With Diabetes?
We're here to help you navigate your journey.

If you’d like to learn more about our diabetes clinical trials, treatment options, or how you can play a role in advancing medical research, our team is ready to support you every step of the way.

Your participation could help shape the future of diabetes care for yourself and for countless others.

📞 Contact us for more info:
📱 021 931 7825
📱 066 472 5713
✉️ info@treadresearch.com

Diabetes Awareness Month 🩸 At TREAD Research, we stand with every fighter, every family, and every heartbeat living with...
16/11/2025

Diabetes Awareness Month 🩸 At TREAD Research, we stand with every fighter, every family, and every heartbeat living with diabetes.

If you’ve been diagnosed with diabetes and would like to learn more about clinical trials or treatment options, our team is here to support you with care, information, and compassion. Your participation could help improve future treatment for countless others. 💙

📩 Contact us for more info:
📞 021 931 7825
📱 066 472 5713
📧 info@treadresearch.com

Address

Room 41, 8th Floor Green Avenue Tygerberg Hospital Francie Van Zijl Drive, Parow
Cape Town
7505

Opening Hours

Monday 08:00 - 15:30
Tuesday 08:00 - 15:30
Wednesday 08:00 - 17:00
Thursday 08:00 - 17:00
Friday 08:00 - 17:00

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