Nova Evolve

11/03/2026

Understanding how lipid accumulation affects liver cells is essential for studying metabolic disease and fatty liver disorders.

This research explores how oleic acid can induce steatosis in liver cells, creating a useful in-vitro model to investigate lipid metabolism, triglyceride accumulation, and gene expression changes associated with metabolic stress.

Studies like this help researchers better understand the cellular mechanisms involved in metabolic disease and liver dysfunction.

Article:

11/03/2026

Researchers studying fatty liver disease often use HepG2 liver cells treated with sodium oleate to simulate lipid accumulation in vitro.

These experimental models help scientists investigate metabolic disease mechanisms such as lipid metabolism, oxidative stress, and insulin resistance.

It’s always interesting to see how different laboratories approach MASLD and metabolic disease research.

22/12/2025

At Nova Evolve, we focus on supporting high-quality biomedical research by facilitating access to reliable, well-validated research reagents.

We are encouraged to see lipid reagents supplied by Kunchuang Biotechnology used in peer-reviewed research published in Oncogenesis (Nature Portfolio), contributing to established experimental models in metabolic and oncology research.

We look forward to supporting researchers and institutions working in lipid metabolism, cell biology, and related fields.

Published article:

The deubiquitinating enzyme Ubiquitin specific peptidase 5 (USP5) has attracted substantial notice for its vital role in cancer progression. However, the USP5-mediated deubiquitination of corresponding protein substrates and its functional role in hepatocellular carcinoma (HCC) have not been fully i...

10/12/2025