24/03/2026
Tuberculosis (TB):
An Overview
What is Tuberculosis?
Tuberculosis (TB) is a contagious infectious disease caused by the bacterium Mycobacterium tuberculosis. It mainly affects the lungs (pulmonary TB) but can also affect other parts of the body such as the spine, kidneys, brain, and lymph nodes (extrapulmonary TB).
TB remains one of the leading infectious causes of death worldwide, particularly in countries such as South Africa.
How TB Spreads
TB spreads through the air when a person with active pulmonary TB:
Coughs
Sneezes
Talks
Sings
Tiny droplets containing TB bacteria are inhaled by others nearby.
TB is not spread by:
Sharing utensils
Touching
Kissing
Sharing clothes or bedding
Types of TB
1. Latent TB Infection
The bacteria are in the body but inactive.
The person has no symptoms.
The person is not contagious.
It can become active later if immunity weakens.
2. Active TB Disease
The bacteria multiply and cause symptoms.
The person may spread TB to others.
Requires immediate treatment.
Symptoms of Active Pulmonary TB
Persistent cough (lasting more than 2 weeks)
Coughing up blood (haemoptysis)
Chest pain
Night sweats
Fever
Weight loss
Fatigue
Loss of appetite
Extrapulmonary TB symptoms depend on the organ affected.
TB and HIV
TB is especially dangerous in people living with HIV because their immune systems are weakened. In countries like South Africa, TB and HIV co-infection is common.
People with HIV are more likely to:
Develop active TB
Have severe disease
Experience complications
Diagnosis
TB is diagnosed using:
Sputum tests (GeneXpert / microscopy)
Chest X-ray
Tuberculin skin test (Mantoux)
Blood tests
Biopsy (for extrapulmonary TB)
Early diagnosis is crucial to prevent spread.
Treatment
TB is curable with proper treatment.
Standard treatment:
A combination of antibiotics
Usually taken for 6 months
Must be completed fully
Common TB medications include:
Isoniazid
Rifampicin
Pyrazinamide
Ethambutol
Incomplete treatment can lead to drug-resistant TB (MDR-TB), which is harder and longer to treat.
Prevention
Early detection and treatment
Good ventilation
Covering mouth when coughing
Wearing masks in high-risk settings
TB preventive therapy for high-risk individuals
BCG vaccine (given at birth in many countries)
The World Health Organization promotes global TB control strategies.
When to Seek Medical Care
Seek medical attention if:
You have a cough for more than 2 weeks
You experience unexplained weight loss
You have night sweats and fever
You have been in close contact with someone with TB
Conclusion
Tuberculosis remains a serious but preventable and curable disease. Early diagnosis, proper treatment, and community awareness are key to controlling its spread.