12/01/2026
SAHPRA
South African
Health Products
Regulatory Authority
MEDIA RELEASE
Warning: Selenium and zinc picolinate-containing products for children
South African Health Products Regulatory Authority (SAHPRA) has been made aware of products in the market containing Zinc picolinate (as a source material for zinc) and/or Selenium intended for use in children.
Both of these ingredients have been identified in the Guidance (SAHPRA Guideline 7.04 / SAHPGL-PEM-COMP-04 v5 CM SE Health Supplements) issued by SAHPRA as not permitted in health supplements for children (persons under the age of 18).
The safety concerns related to children are as follows:
1. Zinc picolinate, at any supplemental dose, can cause side effects which include indigestion, diarrhea, headache, nausea, and vomiting. As the bio-availability of Zn from Zn-picolinate is variable due to multiple factors, the risk of side effects may be higher and unpredictable, and it is unsuitable as a source of elemental zinc supplementation in children; and
2. Selenium, when supplemented to children, represents a safety concern considering the potential differences in selenium daily intake between different population groups. While selenium intake is a viable requirement for children in areas of famine or dietary restriction, the potential adverse effects of selenium overdose are of concern when provided in general supplements/medicines intended for children.
Important Exclusions (Products to Avoid)
To ensure you do not accidentally purchase the wrong variation, note that the following common products do contain the ingredients you wish to avoid:
• Zinplex Junior Syrup (Standard/Cream Soda/D3): Contains both Zinc Picolinate and
Selenium.
• Biogen Junior Zinc-mune Syrup: Contains both Zinc Picolinate and Selenium.
• Zinplex Zinc Dispersible Tablets: These contain Zinc Picolinate.
Thank you for updates of what’s available and Paediatric references 🙏