19/04/2026
The ketogenic diet is one of the few nutritional interventions in medicine with consistent, reproducible neurological outcomes.
In drug-resistant epilepsy, seizure reduction is not simply anecdotal it is well documented.
But the mechanism matters.
Ketones:
• increase mitochondrial efficiency
• enhance ATP production
• stabilise neuronal membranes
• increase GABA relative to glutamate (reducing excitability)
• reduce oxidative stress
This shifts the brain from a glucose-dependent, often unstable energy system → to a more stable, regulated metabolic state.
This is not “dieting.”
This is altering brain bioenergetics.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6361831/