12/16/2015
Interesting new research linking the inflammatory protein Zonulin, which regulates permeability in our digestive tract, and the inflammatory bowel conditions irritable bowel syndrome (IBS) and non-celiac gluten sensitivity (NCGS). What does Zonulin do? Well, under normal conditions it is triggered by harmful bacteria to help protect us by flushing out our system. If you've ever had food poisoning, then you know exactly what I mean...It is already known that levels of zonulin are high in celiacs, but this study showed elevated levels in patients with IBS and even higher levels in NCGS that matched the celiac patients. What does this mean? Well, it stands as a possible mechanism to help diagnose, monitor and treat these conditions. However, before people jump on the "Zonulin train", the research is new and limited to one team of researchers, meaning there is a lot more good research that needs to be done.
http://www.eurekalert.org/pub_releases/2015-10/sh-rfn102215.php #.Vm5DRrT5rWw.mailto
Researchers have discovered that people with non-celiac gluten sensitivity (NCGS) and irritable bowel syndrome (IBS) have higher than normal blood levels of zonulin, suggesting an important role for the protein in the development of these conditions.