Center for Complex Neurology, EDS & POTS

Center for Complex Neurology, EDS & POTS The office of David Saperstein, MD. We specialize in EDS, POTS and other disorders of nerve, muscle

The holidays can be a busy time. Here are a few tips to help you enjoy Thanksgiving week while managing your health. 🦃💙 ...
11/25/2025

The holidays can be a busy time. Here are a few tips to help you enjoy Thanksgiving week while managing your health. 🦃💙

🍁 Plan your day to include rest breaks.
🥄 Listen to your body evaluate your energy levels.
💧 Remember to stay hydrated.
🦃 Stick to physician's dietary recommendations.
🍂 Try to communicate your needs to family and friends. ⁣

⁣📲 Share a tip of what has helped you in the past. 💬

🍂 Thanksgiving Week Hours 🍂🕒 Monday - Tuesday: Open🕒 Wednesday - Friday: Closed🕒 Monday: Back to normal hours✨ Heads up:...
11/24/2025

🍂 Thanksgiving Week Hours 🍂

🕒 Monday - Tuesday: Open
🕒 Wednesday - Friday: Closed
🕒 Monday: Back to normal hours

✨ Heads up: Any prescription refills or requests must be submitted by Tuesday morning. Anything submitted after will be handled when we return on Monday.

Wishing you a safe and Happy Thanksgiving week!

11/23/2025

Mast cells 🩸 are a type of white blood cell that plays an essential role in the body’s immune system, particularly in allergic reactions 🤧 and defense against pathogens 🦠. They are part of the immune system’s first line of defense 🛡️ and are found in various tissues throughout the body, including the skin, lungs, and digestive tract. 💪✨

11/21/2025

What is Long Covid?

Symptoms that last for more than 2 months after COVID-19 infection are referred to as “Long Covid” or “post-acute sequelae of SARS-CoV-2 (PASC).” 10-30% of people infected with COVID-19 will experience persisting problems.

There are specialized tests that will usually show problems in those with Long Covid. In particular, autonomic testing often shows abnormal changes in heart rate, blood pressure, or blood flow. Recent studies have shown that patients with Long Covid frequently will have abnormal results on autonomic testing, exercise testing (which measures how well the body utilizes oxygen), and skin biopsy measurement of small nerve fibers. In addition, specialized blood and urine tests can identify problems with mast cells or the immune system.

It is common for us to see patients who have been to multiple doctors and were told there was nothing wrong, or no diagnosis could not be determined. It is common for patients to be shuffled among numerous different specialists.

Visit our website to learn more about Long Covid.


🔎 When the autonomic nerves don’t function properly in Dysautonomia, the GI tract can be seriously affected. Symptoms ma...
11/20/2025

🔎 When the autonomic nerves don’t function properly in Dysautonomia, the GI tract can be seriously affected. Symptoms may include:
🔹 Nausea
🔹 Vomiting
🔹 Constipation
🔹 Diarrhea
🔹 Abdominal Pain
🔹 Gastroparesis
🔹 Weight Loss
🔹 Malnutrition
🔹Weight Gain
🔹and MORE!

🩺 Dysautonomia is often invisible, misunderstood, and under-recognized. Having the right physicians matters. With over 20 years of experience, Dr. Saperstein specializes in diagnosing and managing Dysautonomia so patients can get real answers and real support.

💡 Were you surprised that Dysautonomia can affect the entire digestive system? 💬 Have YOU experienced any of these GI symptoms with Dysautonomia?

🔁 Share this post to spread awareness about Dysautonomia.
📌 Save it to revisit or educate others later.
❤️ Like to help this reach more people.

💡 Did you know? Salt is an electrolyte! ⚡ An electrolyte is a substance that conducts an electrical current when in wate...
11/18/2025

💡 Did you know? Salt is an electrolyte! ⚡ An electrolyte is a substance that conducts an electrical current when in water. In our bodies, water dissolves salt, activating nerves and muscles.

For many Dysautonomia patients, salt is more than just a seasoning—it's a game-changer! 🧂💧 Salt is a nonpharmacological treatment option for many Dysautonomia patients. Salt is needed to help the body retain water. Greater sodium in the diet and increased water intake help maintain equilibrium and increase blood pressure.

Want to dive deeper into how salt can help Dysautonomia? Check out Dr. David Saperstein’s expert insights in our latest Salt Supplementation video! 🎥✨
🔗 https://bit.ly/SaltSupplementationVideo

Save this post for later, share it with someone who could benefit, and follow us for more tips!

✨ A Patient’s EDS Journey Can Often Look Like This. When a patient tells a physician or other provider that they think t...
11/18/2025

✨ A Patient’s EDS Journey Can Often Look Like This. When a patient tells a physician or other provider that they think they might have EDS, many times they are told that’s probably not the case simply because that’s a very uncommon condition to have. The larger problem leading to difficulties in diagnosis is that so many different things can happen with EDS and they can resemble other more common conditions.

⚕️ So, if you’re a specialist in one condition, you’re going to tend to focus on what you specialize in and focus on some set of symptoms and maybe underappreciate other symptoms. Similar to the old parable talking about several blind men who were trying to determine what an elephant was like just based on touching it. So, based on what part of the elephant they happen to touch, they decided this is what an elephant was.

🩻 If we substitute these literal structures of the elephant and talk about the features of EDS, you can see that based on the symptoms that someone focuses on or what their specialty is, they may decide the patient has one thing and not see the larger picture. EDS has many faces and can present in many ways and it can make it difficult to diagnose.

🩺 At the Center, we are dedicated to the care of patients with complex neurological problems which include Ehlers-Danlos Syndrome. We provide diagnostics and treatment to help patients live full and active lives despite this challenging disorder.

Check out Dr. Saperstein’s in-depth video about this on our website.
https://bit.ly/LearnMore_EDS

🧬 Why Do Mast Cells Matter in MCAS (Mast Cell Activation Syndrome)?Mast cells are part of your immune system and they’re...
11/16/2025

🧬 Why Do Mast Cells Matter in MCAS (Mast Cell Activation Syndrome)?

Mast cells are part of your immune system and they’re supposed to protect you. But in MCAS, they go a little haywire…

Instead of reacting to real threats, they release chemicals (like histamine) too easily, causing symptoms all over your body like:
🔷 Flushing or hives
🔷 Gut issues
🔷 Brain fog
🔷 Shortness of breath
🔷 Dizziness

The problem isn’t how many mast cells you have, it’s how they’re acting. Overreactive mast cells = chronic symptoms that can be hard to pin down.

🎯 Treating MCAS means calming down those mast cells and identifying what’s triggering them.

📌 Save this to come back to later.
📧 Share with someone who’s still searching for answers.
📲 Visit our website to learn more.
https://bit.ly/LearnMoreAbout_MCAS

🤯 Did You Know? ⁉️ About 50% of patients with EDS (Ehlers-Danlos Syndrome) can touch the tip of the nose with their tong...
11/15/2025

🤯 Did You Know? ⁉️ About 50% of patients with EDS (Ehlers-Danlos Syndrome) can touch the tip of the nose with their tongue. 🦓 In medical terms it’s called Gorlin’s sign. 🩺 It’s estimated that only 10% of the general population can do this.

Which one are you?! 🔎💬
🔷 A. Can touch my nose
🔷 B. Can’t touch my nose

🧠 Chiari Malformation (CM) is a condition where brain tissue extends into the spinal canal. It causes structural defects...
11/14/2025

🧠 Chiari Malformation (CM) is a condition where brain tissue extends into the spinal canal. It causes structural defects in the base of the skull and cerebellum. When a part of the cerebellum extends below the foramen magnum and into the upper spinal canal, it is referred to as a Chiari Malformation. ❤️‍🩹

🩺 Symptoms can include headache, balance problems, and troubles with vision and swallowing. In most patients, symptoms can be managed with medications, but sometimes surgery is needed. 💊

⚕️At the Center, Dr. Saperstein and his team will make an assessment of your Chiari Malformation and guide you through the most appropriate and effective treatment for your condition.

📍 Head to our website to learn more about Chiari Malformation or to watch Dr. Saperstein’s videos. https://bit.ly/Chiari_Malformation

✨ Cranial Cervical Instability (CCI) happens when the ligaments supporting your head and neck weaken or get damaged, cau...
11/13/2025

✨ Cranial Cervical Instability (CCI) happens when the ligaments supporting your head and neck weaken or get damaged, causing everything from chronic headaches and neck pain to vertigo and even cognitive challenges. 🧠💫 Often linked to conditions like Ehlers-Danlos Syndrome, trauma, or spine changes, CCI can be treated with physical therapy, medication, or in severe cases, surgery.

🩺 Dr. Saperstein has over 20 years of experience diagnosing and treating CCI, using medical imaging to find the best approach for each patient.

💬 Have you or someone you know been impacted by CCI?
⬇️ Drop a 💙 in the comments to help raise awareness.
👥 Tag someone who needs to see this.
📲 Share this post to spread awareness.
❤️ Like to help this reach more people.

11/12/2025

🧬 A Brief History of Ehlers-Danlos Syndrome (EDS)

From Hippocrates describing unusual bruising in 400 BC, to the modern diagnostic criteria established in 2017, the story of EDS spans centuries of discovery and resilience. 💜

Each milestone brought greater understanding, but awareness still has a long way to go.

💬 Are you shocked by how under-recognized this condition remains after all these years?
📲 Share this post to spread awareness.
👥 Tag someone who needs to see this.

⁣⁣

Address

1010 E McDowell Road. , Suite 101
Phoenix, AZ
85006

Opening Hours

Monday 8am - 4pm
Tuesday 8am - 4pm
Thursday 8am - 4pm
Friday 8am - 4pm

Telephone

+16029009404

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Category

Center for Complex Neurology

We provide expert diagnosis and treatment of selected diseases, to include ALS, CIDP, Ehlers-Danlos Syndrome, (EDS), GBS, Neuropathy, Myositis, Muscular Dystrophy, Myasthenia Gravis, POTS & other dysautonomias. Dr. Saperstein has over 20 years of experience diagnosing, treating and researching these conditions.

Why did I create the Center for Complex Neurology?

Over the last 22 years I have been practicing medicine I have done so in a variety of settings: on staff at a university medical center, in private practice, as part of a health care system, and even in the U.S. military (Air Force). Each system had it pluses and minuses. But all forms of medical practice have come under strain in recent years from unprecedented changes in the health care system.